KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
23.64
Human Site:
S807
Identified Species:
40
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S807
A
W
L
D
Q
Y
C
S
L
P
A
L
R
P
T
Chimpanzee
Pan troglodytes
XP_509441
819
90122
S773
S
W
L
D
Q
H
C
S
L
P
I
L
R
P
M
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
L346
W
L
D
Q
Y
C
S
L
P
A
L
R
P
T
V
Dog
Lupus familis
XP_546925
857
93734
S812
A
W
L
D
Q
Y
C
S
L
P
A
L
R
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S819
A
W
L
E
Q
Y
C
S
L
P
A
L
R
P
T
Rat
Rattus norvegicus
Q6AXT8
471
49872
P427
G
V
H
P
Q
P
P
P
G
V
H
P
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
G851
S
F
S
R
G
S
V
G
D
A
W
R
G
H
A
Frog
Xenopus laevis
NP_001084764
548
60887
A504
I
A
I
S
K
P
G
A
K
H
K
A
K
P
Q
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
S771
Q
W
L
D
R
Y
C
S
L
P
A
L
R
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
S786
L
W
V
D
Q
H
C
S
L
I
D
L
R
P
A
Honey Bee
Apis mellifera
XP_394429
1014
115124
S968
L
W
V
E
Q
H
C
S
L
V
D
L
R
P
A
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
C960
R
N
E
V
A
A
S
C
S
D
W
L
N
K
N
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
N1294
R
P
L
F
E
S
F
N
S
T
V
S
T
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
I1081
L
M
H
Y
L
C
K
I
L
A
E
K
I
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
73.3
0
100
N.A.
93.3
6.6
N.A.
N.A.
0
6.6
80
N.A.
60
53.3
6.6
13.3
P-Site Similarity:
100
86.6
0
100
N.A.
100
6.6
N.A.
N.A.
13.3
33.3
86.6
N.A.
73.3
73.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
0
0
8
8
0
8
0
22
29
8
8
8
22
% A
% Cys:
0
0
0
0
0
15
50
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
36
0
0
0
0
8
8
15
0
0
0
0
% D
% Glu:
0
0
8
15
8
0
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
8
8
8
0
0
0
8
0
0
% G
% His:
0
0
15
0
0
22
0
0
0
8
8
0
0
8
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
8
8
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
8
0
8
8
8
8
0
% K
% Leu:
22
8
43
0
8
0
0
8
58
0
8
58
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
8
% N
% Pro:
0
8
0
8
0
15
8
8
8
36
0
8
8
65
8
% P
% Gln:
8
0
0
8
50
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
15
0
0
8
8
0
0
0
0
0
0
15
50
0
0
% R
% Ser:
15
0
8
8
0
15
15
50
15
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
29
% T
% Val:
0
8
15
8
0
0
8
0
0
15
8
0
0
0
8
% V
% Trp:
8
50
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
8
8
29
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _